Klonopin is used to treat disorders including panic disorder, seizures, restless leg syndrome, anxiety disorder and fibromyalgia.
The exact working mechanism of Klonopin is not known. Likewise, the effects at withdrawal also are not fully understood. However, the sedation induced and withdrawal symptoms caused by Klonopin vary patient to patient.
Particularly, if the patient is on other medications, alcohol, or illicit drugs, it becomes complicated. The speed of nerve cells’ functions also can differ with patients.
For example, the split-second firing of nerve cells in the brain is slow in some patients and fast in some patients.
Some patients are relieved of the withdrawal symptoms caused by Klonopin if they just take a mild antidepressant. Kava and melatonin can be of much help to these patients.
The half life of Klonopin is 35 hours. This implies that half of Klonopin is still circulating in your blood after 35 hours. After another 35 hours, there is around one quarter of Klonopin consumed in one dose.
It is important to remember that all these calculations apply only to one dose. So, if you are on a constant Klonopin dose, your body has accumulated Klonopin levels over a period of time.
This accumulation is necessary to supplement your body with a steady and optimal dosage needed to treat the disorder. Therefore, this accumulated Klonopin level functions to slow down the brain activity.
The dampening of the brain activity is achieved by reduced rate of firing of the brain cells. This function is similar to that of Valium, which prevents the brain from over-firing.
GABA is a natural chemical available in the brain that suppresses the excess neuron activity. This means that you are saved from any anxiety related disorders if the level of GABA is maintained correctly.
GABA has the capability to calm down one’s body. Klonopin acts as a supplement to this function. It helps GABA to work more effectively.
For patients who have been under the dosage of Klonopin over an extended period of time or using large doses, stomach pain and leg cramps are a few of the symptoms that one could experience when sudden withdrawal is attempted.
Seizures and anxiety with insomnia can increase for people who have been under low dosage for a short time. Fatigue is generally not observed as a side effect of withdrawal of Klonopin.
Brain makes a religious effort in maintaining various parameters such as hormone levels, glucose levels, brain chemicals, acid-base levels, body temperature etc. This process is described as homeostasis.
This process helps to increase or decrease the levels of hormones or chemicals as when required. Since, Klonopin is involved in the activity that GABA is supposed to perform, insufficient levels of GABA is exhibited.
When Klonopin is suddenly stopped, brain must reorganize its functions to restore the level of GABA in the brain. This process takes time and until then the patient may experience the symptoms arising due to low levels of GABA.
Klonopin belongs to a family of drugs called benzodiazepines which is a very efficient muscle relaxant.
Drugs under this family are also used to treat muscle spasms. When Klonopin is suddenly stopped, the body experiences a rebound effect. This implies that muscles get very taut leading to aches and hyper excitability.
This effect is manifested as fatigue in a few patients. The hyper excitation is due to the over production of hormones like adrenaline and noradrenalin.
GABA is also found to influence production of human growth hormone used for the growth of the muscle. Therefore, for the above reasons, it is advisable to gradually stop the use of Klonopin.
Gradual reduction of Klonopin will give the brain its time to restore its normal function instead of leaving it hungry for hormones. Remember, brain is the master of the body. Conserving it and its activity is of critical importance to one’s well being.